Clinical Component

Acting Clinical Component Director: Paul Monga, MD

The Clinical Component of the PLRC assists investigators at different time points in their research process. During the conceptual stage of their project, it will help PIs to select clinically meaningful end-points, appropriate use of clinical phenotypes, and accurate power calculations with robust statistical analysis. During the execution stage of the project, it will advise investigators on adequate use of the PLRC Cores with a clinically meaningful study design, including the selection of appropriate human biospecimens, and a cost-effective use of high throughput -omics techniques.

The Clinical Consulting Committee is comprised of clinicians who specialize in the liver diseases such as: 
  • Non-alcoholic liver disease
  • Alcoholic liver disease
  • Endocrinology
  • Viral hepatitis
  • Cirrhosis
  • Genetic diseases and cholestasis
  • Portal hypertension
  • Critically-ill cirrhotic patients
  • Transplant hepatology
  • Pediatric hepatology
  • Liver Transplantation
  • Liver cancer
PLRC investigators who would like to discuss their projects with the Clinical Consulting Committee can initiate a meeting by contacting Dr. Ramon Bataller (
The Clinical Component partners with:
The Coulter Program (Scott Morley, MBA):  As part of the Clinical Component, the Coulter Program will provide support in evaluating proposed technologies, including assessments of commercial readiness, value analysis relative to existing standards of care, mapping of regulatory and reimbursement pathways, stakeholder analysis, and clinician adoption modeling.