Innovative Collaborative Resources

Please contact the relevant PI directly to discuss possible collaborations.

 Bile duct ligation

 Kari Nejak-Bowen

 Body composition by proton-NMR

 Michael Jurczak

 cGMP cellular product manufacture

 Lisa Butterfield, Director of UPCI Immunologic Monitoring and Cellular Products Laboratory
http://upci.upmc.edu/imcpl/

 Special chemistry lab in the CLB (Pathology): offers assays for several drugs and vitamins; provides consultation for preclinical and clinical drug study designs.

 Raman Venkataramanan

 Drug Discovery Institute: collaborates with faculty interested in including drug discovery, development and computational pathology in their research programs

 Lans Taylor, Director of University of Pittsburgh Drug Discovery Institute
https://www.upddi.pitt.edu/

 Flow Cytometry

 Eric Lagasse

 Hepatocyte culture work – In vitro

 Raman Venkataramanan

 Histology, basic

 Sarangarajan Ranganathan (through CHP Pathology Division, research core laboratory)

 Hyperinsulinemic euglycemic clamp with isotopic tracers

 Michael Jurczak

 Imaging — Ultrasound Thermal Strain

 Imaging — Micro-vasculature network in vivo at high resolution

 Kang Kim

 Immune assay development and conduct

 Lisa Butterfield, Director of UPCI Immunologic Monitoring and Cellular Products Laboratory
http://upci.upmc.edu/imcpl/

 Immunohistochemical support for workup of antibodies 

 Sarangarajan Ranganathan (through CHP Pathology Division, research core laboratory)

 In vitro microfluidic platforms to test molecular targets in patient blood samples

 Prithu Sundd

 In vivo animal studies

 Raman Venkataramanan

 Inflammation biomarker analyses (e.g. Luminex™, ELISA, etc.) 

 Yoram Vodovotz

 Isolated Liver perfusion

 Raman Venkataramanan

 Liver perfusion

 Kari Nejak-Bowen

 Magnetic activated cell sorter [Miltenyi Biotec]: magnets (Mini, Midi, and QuadroMACS) with stands 

 Eva Schmelzer, in collaboration with Joerg Gerlach

 Metabolomic analysis. We provide both untargeted metabolomics (global metabolites) and targeted metabolomics (such as bile acids, drugs, and drug metabolites).

 Xiaochao Ma

 Laser capture microdissection

 Michael Oertel

 Metabolic cage analysis for energy expenditure, feeding and activity

 Michael Jurczak

 Microscopy – Intravital in live mice

 Microscopy – Live cell

 Microscopy – Total internal reflection fluorescence

 Prithu Sundd   

 

 NexGen sequencing

 Obaid Shaikh, in collaboration with Dr Scott Kulich (Chief of Molecular Anatomic Pathology at the VA)

 Odyssey Infrared Scanner [Licor]

 Eva Schmelzer, in collaboration with Joerg Gerlach

 Proteomics

 Nathan Yates

 Real-time PCR [Applied Biosystems]

 Eva Schmelzer, in collaboration with Joerg Gerlach

 Recruitment of patients for clinical studies and for the collection of samples used to further understand and explore hepatobiliary diseases affecting children

 James Squires

 Software and analytic support for quantitating muscle mass on cross sectional imaging. 

 Michael Dunn

 Tissue and blood banking 

 Lisa Butterfield, Director of UPCI Immunologic Monitoring and Cellular Products Laboratory
http://upci.upmc.edu/imcpl/

 Tissue Processing

 Sarangarajan Ranganathan (through CHP Pathology Division, research core laboratory)

 IRB-approved pathway available for faculty colleagues who may want to explore clinical applications of wearable physical activity monitoring.

 Michael Dunn