Liver Center Resources

PLRC members have identified the following resources in their clinics and labs, which may be useful to other PLRC members. If you would like to use a resource listed below, please contact the investigator listed next to the resource.

Cell Lines

 Hep3B

 Kari Nejak-Bowen

 HepG2

 Kari Nejak-Bowen

 AML12

 Kari Nejak-Bowen

 primary mouse hepatocytes

 Kari Nejak-Bowen

 Raw264.7

 Kari Nejak-Bowen

 sm-cc (mouse-derived immortalized cholangiocytes)

 Kari Nejak-Bowen

Animal Models

Mouse models

 ATPIF1 knockout

 Michael Jurczak

 ATPIF1fl/fl

 Michael Jurczak

 Cre recominase under an alpha feto protein enhancer driven albumin promoter (Afp/Alb)

 Wendy Mars, in collaboration with George Michalopoulos

 Fah-KO (C57BL/6 background)

 Andrew Duncan

 FRGN (Fah-KO, Rag2-KO, Interleukin-2 common gamma chain-KO, NOD background)  Andrew Duncan

 Glypican transgenic under an albumin promoter

 Wendy Mars, in collaboration with George Michalopoulos

 HGF flox crossed with a cre recombinase under an inducible tamoxifen promoter

 Wendy Mars, in collaboration with George Michalopoulos

 HGF transgenic under a GFAP promoter

 Wendy Mars, in collaboration with George Michalopoulos

 Integrin Linked Kinase (ILK) flox 

 Wendy Mars, in collaboration with George Michalopoulos

 Kindlin 2 flox crossed with the Afp/Alb cre recombinase

 Wendy Mars, in collaboration with Cary Wu

 LRP1 flox crossed with the Afp/Alb cre recominase

 Wendy Mars, in collaboration with George Michalopoulos

 Lymphocyte Specific Protein 1 (LSP1) knockout 

 Wendy Mars, in collaboration with George Michalopoulos

 LSP1 transgenic under an albumin promoter

 Wendy Mars, in collaboration with George Michalopoulos

 Mdr2 KO (FVB background) 

 Kari Nejak-Bowen

 Mdr2 KO (C57Bl/6 background) tamoxifen inducible Sox9-Cre  Kari Nejak-Bowen

 MET flox crossed with a cre recombinase under an inducible tamoxifen promoter

 Wendy Mars, in collaboration with George Michalopoulos

 MET flox crossed with the Afp/Alb cre recominase

 Wendy Mars, in collaboration with George Michalopoulos

 MET flox crossed with a lysZ cre recominase

 Wendy Mars, in collaboration with George Michalopoulos

 Mito-Keima (mitophagy reporter line)

 Michael Jurczak

 PARK2flfl/Albcre+/-

 Michael Jurczak

 PARK2flfl/Vilcre+/-

 Michael Jurczak

 PARK2 knockout

 Michael Jurczak

 S45D β-catenin-mutated mice (C57Bl/6 background)

 Kari Nejak-Bowen

 u-PA knockout

 Wendy Mars, in collaboration with George Michalopoulos

 u-PA receptor knockout

 Wendy Mars, in collaboration with George Michalopoulos

Rat models

 DPPIV+ F344

 Michael Oertel

 DPPIV- F344

 Michael Oertel